© Pint of Science, 2024. All rights reserved.
Welcome to Volta Bräu for the 1st day of Pint of Science in Basel
Program
18:00-18:20 Doors open
18:20-18:30 Presentation of Pint of Science
18:30-19:00 Talk of Alina Gavrilov "Using our immune system to eliminate tumors"
Short break
19:05-19:35 Talk of Gray Camp "Organoids to explore the human condition"
Short break
19:40-20:10 Talk of Nassim Rousset "Your body on a chip: Better preclinical models with microfluidics"
20:10-20:30 Quiz for the audience & Closing of the night
For any question please do not hesitate to contact us: [email protected]
Program
18:00-18:20 Doors open
18:20-18:30 Presentation of Pint of Science
18:30-19:00 Talk of Alina Gavrilov "Using our immune system to eliminate tumors"
Short break
19:05-19:35 Talk of Gray Camp "Organoids to explore the human condition"
Short break
19:40-20:10 Talk of Nassim Rousset "Your body on a chip: Better preclinical models with microfluidics"
20:10-20:30 Quiz for the audience & Closing of the night
For any question please do not hesitate to contact us: [email protected]
Using our inmune system to eliminate tumors
Alina Gavrilov, M.Sc.
(Principal Associate at Roche )
To investigate the poorly understood biological processes of the blood-brain barrier (BBB), we established a standardized 3D in vitro model of the BBB. Furthermore, to investigate the impact of disease, we developed a BBB-tumor model. We successfully embedded tumor cells into the BBB organoid core. At Roche new therapeutics are constantly developed, one of them being T cell bispecific antibodies. In this talk, I will explain how we can use those new technologies to trigger our own immune system to eliminate tumors.
Organoids to explore the human condition
Dr Gray Camp
(Research Group Leader, Institute for Translational Bioengineering ITB, Roche)
Using organoids to understand human physiology
Your body on a chip: Better preclinical models with microfluidics
Nassim Rousset, M.Sc.
(Doctorate Student, D-BSSE, ETH Zürich)
I will introduce the world of microphysiological systems and their potential to replace animal models. Microphysiological systems use microfluidics to connect microscopic organ models in a manner that is relevant for drug development. For example, you could connect a liver and gut model - our principal organs for drug metabolism - to a cancer model. Then, by dosing a certain compound through the metabolizing organs, you could measure its therapeutic effect on cancer. These so-called “body-on-a-chip” would be more relevant than traditional tests on isolated organ models in Petri dishes.
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